Superoxide Dismutase 2, Mitochondrial (SOD2) (N-Term) Peptide
SOD2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN984231
Aperçu rapide pour Superoxide Dismutase 2, Mitochondrial (SOD2) (N-Term) Peptide (ABIN984231)
Antigène
SOD2
(Superoxide Dismutase 2, Mitochondrial (SOD2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SOD2 antibody (Catalog #: ARP58529_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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Sujet
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SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene encoding SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: IPO-B, MNSOD, Mn-SOD, IPOB, MVCD6
Protein Interaction Partner: GET4,HDHD2,NOL12,RAB4A,RPS3A,SOD2,AURKA,NOL12,RPS3A
Protein Size: 222 -
Poids moléculaire
- 24 kDa
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ID gène
- 6648
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NCBI Accession
- NM_000636, NP_000627
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UniProt
- P04179
Antigène
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