SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) Peptide
SOX2
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN984265
Aperçu rapide pour SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) Peptide (ABIN984265)
Antigène
SOX2
(SRY (Sex Determining Region Y)-Box 2 (SOX2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SOX2 antibody (Catalog #: ARP31737_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Sujet
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SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANOP3, MCOPS3, MGC2413
Protein Interaction Partner: NR5A1,POU2F1,POU5F1,PAX6,POU5F1
Protein Size: 317 -
Poids moléculaire
- 34 kDa
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ID gène
- 6657
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NCBI Accession
- NM_003106, NP_003097
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UniProt
- P48431
Antigène
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