Sperm Acrosome Associated 1 (SPACA1) (N-Term) Peptide
SPACA1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN984304
Aperçu rapide pour Sperm Acrosome Associated 1 (SPACA1) (N-Term) Peptide (ABIN984304)
Antigène
SPACA1
(Sperm Acrosome Associated 1 (SPACA1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- TENNDSETAE NYAPPETEDV SNRNVVKEVE FGMCTVTCGI GVREVILTNG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SPACA1 Antibody(ARP49984_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
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Sujet
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The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Alias Symbols: MGC32952, SAMP32
Protein Size: 294 -
Poids moléculaire
- 32 kDa
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ID gène
- 81833
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NCBI Accession
- NM_030960, NP_112222
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UniProt
- Q9HBV2
Antigène
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