Sjogren Syndrome Antigen B (SSB) Peptide
Aperçu rapide pour Sjogren Syndrome Antigen B (SSB) Peptide (ABIN984447)
Antigène
Origine
Source
Application
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SSB antibody (Catalog #: ARP40462_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SSB (Sjogren Syndrome Antigen B (SSB))
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Sujet
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SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE, MIM 152700) (Teplova et al., 2006).[supplied by OMIM].
Alias Symbols: La, LARP3
Protein Interaction Partner: HCVgp1,SNORD3A,NCL,SSB,NCL,PMVK,PUF60
Protein Size: 408 -
Poids moléculaire
- 45 kDa
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ID gène
- 6741
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NCBI Accession
- NM_003142, NP_003133
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UniProt
- P05455
Antigène
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