SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptide
SWAP70
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN984655
Aperçu rapide pour SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptide (ABIN984655)
Antigène
SWAP70
(SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SWAP70 antibody (Catalog #: ARP46214_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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Sujet
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Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: CELSR3,IGHG1,PARP1,NCL,NPM1,PARP1
Protein Size: 585 -
Poids moléculaire
- 69 kDa
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ID gène
- 23075
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NCBI Accession
- NM_015055, NP_055870
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UniProt
- Q9UH65
Antigène
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