TAP Binding Protein (Tapasin) (TAPBP) (N-Term) Peptide
TAPBP
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN984765
Aperçu rapide pour TAP Binding Protein (Tapasin) (TAPBP) (N-Term) Peptide (ABIN984765)
Antigène
TAPBP
(TAP Binding Protein (Tapasin) (TAPBP))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- GKGLAKRPGA LLLRQGPGEP PPRPDLDPEL YLSVHDPAGA LQAAFRRYPR
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TAPBP Antibody(ARP45436_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
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Sujet
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TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.
Alias Symbols: NGS17, TAPA, TPN, TPSN
Protein Interaction Partner: CALR,COPB1,COPG,COPG2,HLA-A,HLA-C,TAP1,TAP2,CALR,COPB1,COPG,HLA-A,TAP1,TAP2
Protein Size: 299 -
Poids moléculaire
- 30 kDa
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ID gène
- 6892
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NCBI Accession
- NM_172208, NP_757345
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UniProt
- O15533
Antigène
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