Carabin (TBC1D10C)
(TBC1 Domain Family, Member 10C (TBC1D10C))
Protein Region
N-Term
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-TBC1D10C antibody (Catalog #: ARP55893_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
TBC1D10C
Reactivité: Humain
Hôte: Synthetic
BP, BI
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
Carabin (TBC1D10C)
(TBC1 Domain Family, Member 10C (TBC1D10C))
Synonymes
CARABIN Peptide, EPI64C Peptide, 1810062O14Rik Peptide, AI428527 Peptide, RGD1311490 Peptide, TBC1 domain family member 10C Peptide, TBC1 domain family, member 10c Peptide, TBC1 domain family, member 10C Peptide, TBC1D10C Peptide, Tbc1d10c Peptide
Sujet
TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].
Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN