TBP-Like 1 (TBPL1) Peptide
TBPL1
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN984812
Aperçu rapide pour TBP-Like 1 (TBPL1) Peptide (ABIN984812)
Antigène
TBPL1
(TBP-Like 1 (TBPL1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TBPL1 antibody (Catalog #: ARP35751_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TBPL1 (TBP-Like 1 (TBPL1))
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Sujet
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Alias Symbols: TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620
Protein Interaction Partner: ABCF3,C2orf18,GTF2A1,GTF2A2,GTF2B,IRAK4,NDUFA6,NF1,PLIN3,PTCD3,RAB35,RPL10,GTF2A1,GTF2A2,GTF2B,HSPA9,NDUFA6,PMVK,RAB35,RPL10,TAF1,TAF1L,TAF4,TAF5,TAF6,TBP,TBPL2
Protein Size: 186 -
Poids moléculaire
- 21 kDa
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ID gène
- 9519
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NCBI Accession
- NM_004865, NP_004856
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UniProt
- P62380
Antigène
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