Transcription Factor A, Mitochondrial (TFAM) Peptide
Aperçu rapide pour Transcription Factor A, Mitochondrial (TFAM) Peptide (ABIN984970)
Antigène
Origine
Source
Application
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TFAM antibody (Catalog #: ARP36992_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Sujet
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Size: 243 -
Poids moléculaire
- 27 kDa
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ID gène
- 21780
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NCBI Accession
- NM_009360, NP_033386
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UniProt
- P40630
Antigène
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