Transcription Factor B2, Mitochondrial (TFB2M) (N-Term) Peptide
TFB2M
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits TFB2M
- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- MWIPVVGLPR RLRLSALAGA GRFCILGSEA ATRKHLPARN HCGLSDSSPQ
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TFB2M Antibody(ARP39549_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Transcription Factor B2, Mitochondrial (TFB2M) peptide
TFB2M Reactivité: Humain Hôte: Synthetic BP, Imm
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
- Synonymes
- CG3910 Peptide, Dmel\\CG3910 Peptide, TFB2 Peptide, d-TF2BM Peptide, d-mtTFB2 Peptide, TFB2M Peptide, sb:cb857 Peptide, hkp1 Peptide, Hkp1 Peptide, mtTFB2 Peptide, mitochondrial transcription factor B2 Peptide, transcription factor B2, mitochondrial Peptide, mtTFB2 Peptide, TFB2M Peptide, tfb2m Peptide, Tfb2m Peptide
- Sujet
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TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Alias Symbols: FLJ22661, FLJ23182, Hkp1, mtTFB2
Protein Interaction Partner: PNP,POLRMT,TFAM,TFB2M,TFAM
Protein Size: 396 - Poids moléculaire
- 45 kDa
- ID gène
- 64216
- NCBI Accession
- NM_022366, NP_071761
- UniProt
- Q9H5Q4
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