Transferrin Receptor (p90, CD71) (TFRC) (N-Term) Peptide
TFRC
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits Transferrin Receptor (TFRC)
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GYLGYCKGVE PKTECERLAG TESPVREEPG EDFPAARRLY WDDLKRKLSE
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TFRC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Synonymes
- Trfr Peptide, LOC100219280 Peptide, tfr Peptide, cd71 Peptide, tfr1 Peptide, trfr Peptide, CD71 Peptide, T9 Peptide, TFR Peptide, TFR1 Peptide, TR Peptide, TRFR Peptide, p90 Peptide, 2610028K12Rik Peptide, AI195355 Peptide, AI426448 Peptide, AU015758 Peptide, E430033M20Rik Peptide, Mtvr-1 Peptide, Mtvr1 Peptide, transferrin receptor Peptide, TFRC Peptide, Tfrc Peptide, tfrc Peptide
- Sujet
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TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Alias Symbols: CD71, TFR, TFR1, TRFR, T9, TR, p90
Protein Interaction Partner: ACAP1,TF,ACAP1,CD247,CD4,GABARAP,HFE,RAB5B,RANBP9,TF,TFRC,AI837181,AT5G46630,BST2,GABARAP,HDAC5,HFE,PXK,RYK,SVIP,TF,TFRC,nef
Protein Size: 760 - Poids moléculaire
- 84 kDa
- ID gène
- 7037
- NCBI Accession
- NM_003234, NP_003225
- UniProt
- P02786
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