Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Peptide
TGM2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985039
Aperçu rapide pour Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Peptide (ABIN985039)
Antigène
Transglutaminase 2 (TGM2)
(Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TGM2 antibody (Catalog #: ARP47472_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) peptide
TGM2 Reactivité: Humain Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
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Sujet
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Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TG2, TGC, GNAH, G-ALPHA-h
Protein Interaction Partner: HTT,KPNA4,ACTB,ALDOA,ANXA1,CASP3,EIF5A,FN1,GSTP1,HIST1H2BG,HIST2H2BE,HTT,ITGB1,ITGB3,KPNA3,KPNA4,LTBP1,MAP3K12,PLCD1,PPHLN1,RB1,RHOA,S100A7,SERPINF2,SMAD2,SMAD3,SPARC,TGM2,TMSB4X,TUBB,FN1,GSTP1,KPNA4,PLCD1,RB1,TGM2
Protein Size: 687 -
Poids moléculaire
- 77 kDa
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ID gène
- 7052
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NCBI Accession
- NM_004613, NP_004604
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UniProt
- P21980
Antigène
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