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Transmembrane Protease, Serine 3 (TMPRSS3) (N-Term) Peptide

TMPRSS3 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN985283

Aperçu rapide pour Transmembrane Protease, Serine 3 (TMPRSS3) (N-Term) Peptide (ABIN985283)

Antigène

TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Origine

Humain

Source

  • 7
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-TMPRSS3 Antibody(ARP57684_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

    Sujet

    This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

    Alias Symbols: DFNB10, DFNB8, ECHOS1, TADG12

    Protein Interaction Partner: EEF1A1,RXRA,EEF1A1,RXRA

    Protein Size: 344

    Poids moléculaire

    37 kDa

    ID gène

    64699

    NCBI Accession

    NM_032405, NP_115781

    UniProt

    Q8WY52
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