Tyrosine Kinase, Non-Receptor, 1 (TNK1) (C-Term) Peptide
TNK1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985328
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Tyrosine Kinase, Non-Receptor, 1 (TNK1) (C-Term) Peptide (ABIN985328)
Antigène
TNK1
(Tyrosine Kinase, Non-Receptor, 1 (TNK1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- EIRQARAVPQ GPPGLPPRPP LSSSSPQPSQ PSRERLPWPK RKPPHNHPMG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TNK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
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Sujet
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The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC46193
Protein Interaction Partner: PLCG1,PLCG1,SFN,TNK1,UBC
Protein Size: 661 -
Poids moléculaire
- 72 kDa
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ID gène
- 8711
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NCBI Accession
- NM_003985, NP_003976
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UniProt
- Q13470
Antigène
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