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Cardiac Troponin I (TNNI3) Peptide

TNNI3 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN985340
  • Antigène Tous les produits TNNI3
    TNNI3 (Cardiac Troponin I (TNNI3))
    Origine
    Humain
    Source
    • 12
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-TNNI3 antibody (Catalog #: ARP41391_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    TNNI3 (Cardiac Troponin I (TNNI3))
    Synonymes
    CMD1FF Peptide, CMD2A Peptide, CMH7 Peptide, RCM1 Peptide, TNNC1 Peptide, cTnI Peptide, CMD1Z Peptide, CMH13 Peptide, TN-C Peptide, TNC Peptide, TNNC Peptide, Tn1 Peptide, TnIc Peptide, ctnIc Peptide, XTnIc Peptide, c-troponin Peptide, cTNT Peptide, cmh7 Peptide, ctni Peptide, tnnc1 Peptide, TNNI3 Peptide, TnI Peptide, cTNI Peptide, AI874626 Peptide, TnC Peptide, cTnC Peptide, tncc Peptide, Tncc Peptide, troponin I3, cardiac type Peptide, troponin C1, slow skeletal and cardiac type Peptide, troponin I, cardiac 3 Peptide, troponin I type 3 (cardiac) Peptide, troponin I3, cardiac type S homeolog Peptide, troponin I3, cardiac type L homeolog Peptide, cardiac troponin I Peptide, troponin C, cardiac/slow skeletal Peptide, TNNI3 Peptide, TNNC1 Peptide, Tnni3 Peptide, tnni3.S Peptide, tnni3.L Peptide, tnni3 Peptide, LOC100462680 Peptide, Tnnc1 Peptide
    Sujet
    Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 is the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CMH7, MGC116817, TNNC1, cTnI, RCM1, CMD2A, CMD1FF

    Protein Interaction Partner: ACTA1,PAPPA,PKD2,PKD2L1,PRKCA,RCAN3,TNNC1,TNNI3,TNNI3K,TNNT1,TNNT2,LYST,PKD2,PKD2L1,TNNC1,TNNI3K,TNNT2

    Protein Size: 210
    Poids moléculaire
    23 kDa
    ID gène
    7137
    NCBI Accession
    NM_000363, NP_000354
    UniProt
    Q59H18
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