Cardiac Troponin T (cTnT) (N-Term) Peptide
cTnT
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985345
Aperçu rapide pour Cardiac Troponin T (cTnT) (N-Term) Peptide (ABIN985345)
Antigène
Cardiac Troponin T2 (cTnT)
(Cardiac Troponin T (cTnT))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TNNT2 antibody (Catalog #: ARP41717_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
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Sujet
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TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the gene encoding TNNT2 have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Alias Symbols: CMH2, CMPD2, MGC3889, TnTC, cTnT, RCM3, LVNC6
Protein Interaction Partner: MAP3K5,PRKCA,TNNC1,TNNI3,TPM1,TNNI3,TPM1
Protein Size: 295 -
Poids moléculaire
- 35 kDa
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ID gène
- 7139
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NCBI Accession
- NM_000364, NP_000355
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UniProt
- A2TDB9
Antigène
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