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Cardiac Troponin T (cTnT) (N-Term) Peptide

cTnT Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN985345
  • Antigène Tous les produits Cardiac Troponin T2 (cTnT)
    Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-TNNT2 antibody (Catalog #: ARP41717_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
    Synonymes
    CMH2 Peptide, CMPD2 Peptide, LVNC6 Peptide, RCM3 Peptide, TnTC Peptide, cTnT Peptide, Tnt Peptide, CTTG Peptide, Ctt Peptide, RATCTTG Peptide, Tnnt3 Peptide, tnnt2 Peptide, CT3 Peptide, si:ch211-136g2.1 Peptide, troponin T2, cardiac type Peptide, troponin T2, cardiac Peptide, troponin T type 2a (cardiac) Peptide, troponin T2, cardiac type L homeolog Peptide, troponin T2e, cardiac Peptide, TNNT2 Peptide, Tnnt2 Peptide, tnnt2a Peptide, tnnt2.L Peptide, tnnt2e Peptide
    Sujet
    TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the gene encoding TNNT2 have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

    Alias Symbols: CMH2, CMPD2, MGC3889, TnTC, cTnT, RCM3, LVNC6

    Protein Interaction Partner: MAP3K5,PRKCA,TNNC1,TNNI3,TPM1,TNNI3,TPM1

    Protein Size: 295
    Poids moléculaire
    35 kDa
    ID gène
    7139
    NCBI Accession
    NM_000364, NP_000355
    UniProt
    A2TDB9
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