Tripartite Motif Containing 24 (TRIM24) (Middle Region) Peptide
TRIM24
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985500
Aperçu rapide pour Tripartite Motif Containing 24 (TRIM24) (Middle Region) Peptide (ABIN985500)
Antigène
TRIM24
(Tripartite Motif Containing 24 (TRIM24))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TRIM24 antibody (Catalog #: ARP34449_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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Sujet
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The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
Protein Interaction Partner: ESR1,AR,CBX1,CBX3,CBX5,ESR1,ESR2,GTF2E1,HNF4A,HSPA1A,NR2F2,NR3C1,NR3C2,PGR,PML,RARA,RXRA,SUMO1,TAF11,TAF1B,TAF1C,TAF7,THRA,TRIM24,TRIM28,TRIM33,VDR,ZNF10,AR,ESR1,GTF2E1,NR3C1,NR3C2,PML,RARA,RXRA,TAF11,TAF7,THRA,TRIM24,TRIM28,TRIM33,ZNF10
Protein Size: 1050 -
Poids moléculaire
- 117 kDa
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ID gène
- 8805
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NCBI Accession
- NM_015905, NP_056989
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UniProt
- O15164
Antigène
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