Tripartite Motif Containing 63 (TRIM63) (Middle Region) Peptide
TRIM63
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985574
Aperçu rapide pour Tripartite Motif Containing 63 (TRIM63) (Middle Region) Peptide (ABIN985574)
Antigène
TRIM63
(Tripartite Motif Containing 63 (TRIM63))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- EQLDKSTKLV ETAIQSLDEP GGATFLLTAK QLIKSIVEAS KGCQLGKTEQ
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TRIM63 Antibody(ARP43365_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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Sujet
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This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Alias Symbols: FLJ32380, IRF, MURF1, MURF2, RNF28, SMRZ
Protein Interaction Partner: MYL2,TRIM63,GMEB1,MYL2,SUMO2,TRIM54,TRIM55,TRIM63,TTN,UBE2I,USP13,AK1,AKR7A2,ALDOA,CKM,Ckm,ENO3,GMEB1,HIBADH,MYL2,MYOT,NEB,NRAP,PDHB,PDK4,PKM2,PYGM,SUMO2,TCAP,TNNC1,TNNI2,TNNT1,TNNT3,TRIM54,TRIM55,TRIM63,TTN,UBE2I,UBE2J1,UBE2U,UQCRC1,USP13
Protein Size: 353 -
Poids moléculaire
- 40 kDa
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ID gène
- 84676
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NCBI Accession
- NM_032588, NP_115977
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UniProt
- Q969Q1
Antigène
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