U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Peptide
U2AF59
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985792
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Peptide (ABIN985792)
Antigène
U2AF2 (U2AF59)
(U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-U2AF2 antibody (Catalog #: ARP40284_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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Sujet
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U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Alias Symbols: U2AF65
Protein Interaction Partner: BAT1,SF1,SF3B1,U2AF1,ATXN1,BEND7,C1orf190,CHIC2,CPSF7,DDX6,DPPA2,DVL2,EPB41,KIAA0907,MAP1B,PRPF40A,PUF60,SF1,SIP1,SMAD5,SRPK1,SRPK2,SRSF1,SRSF11,SRSF2IP,TCERG1,THAP1,U2AF1,WT1,ZRSR2,BEND7,C1orf190,CHIC2,DPPA2,DVL2,KIAA0907,PUF60,RNPS1,SF1,SF3A2,SRPK2,SRSF1,SRSF11,SRSF2IP,TCERG1,THAP1,U2AF1,WT1
Protein Size: 471 -
Poids moléculaire
- 52 kDa
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ID gène
- 11338
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NCBI Accession
- NM_001012478, NP_001012496
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UniProt
- Q96HC5
Antigène
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