Ubiquitin-Conjugating Enzyme E2C (UBE2C) Peptide
UBE2C
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985806
Aperçu rapide pour Ubiquitin-Conjugating Enzyme E2C (UBE2C) Peptide (ABIN985806)
Antigène
UBE2C
(Ubiquitin-Conjugating Enzyme E2C (UBE2C))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-UBE2C antibody (Catalog #: ARP43090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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Sujet
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11,ANAPC2,ENO2,UBE2C,ANAPC2,BUB1B,CDC20,ENO2,MAD2L1,POLM,RNF216,UBASH3B
Protein Size: 179 -
Poids moléculaire
- 20 kDa
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ID gène
- 11065
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NCBI Accession
- NM_007019, NP_008950
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UniProt
- O00762
Antigène
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