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Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (C-Term) Peptide

UBE2V1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN985842

Aperçu rapide pour Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (C-Term) Peptide (ABIN985842)

Antigène

UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Séquence

    GVVDPRAISV LAKWQNSYSI KVVLQELRRL MMSKENMKLP QPPEGQCYSN

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-UBE2V1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

    Sujet

    Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

    Alias Symbols: CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A

    Protein Size: 147

    Poids moléculaire

    16 kDa

    ID gène

    7335

    NCBI Accession

    NM_001032288, NP_001027459

    UniProt

    Q13404
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