Ubiquitin Conjugation Factor E4 B (UBE4B) Peptide
UBE4B
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985851
Aperçu rapide pour Ubiquitin Conjugation Factor E4 B (UBE4B) Peptide (ABIN985851)
Antigène
UBE4B
(Ubiquitin Conjugation Factor E4 B (UBE4B))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-UBE4B antibody (Catalog #: ARP54552_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))
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Sujet
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: E4, HDNB1, KIAA0684, UBOX3, UFD2, UFD2A
Protein Interaction Partner: CASP3,CASP6,CASP7,DNAJC7,GZMB,VCP
Protein Size: 1302 -
Poids moléculaire
- 146 kDa
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ID gène
- 10277
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NCBI Accession
- NM_001105562, NP_001099032
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UniProt
- O95155
Antigène
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