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Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (N-Term) Peptide

UCP1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN985889

Aperçu rapide pour Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (N-Term) Peptide (ABIN985889)

Antigène

UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Origine

Humain

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    GLPAGLQRQI SSASLRIGLY DTVQEFLTAG KETAPSLGSK ILAGLTTGGV

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-UCP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

    Sujet

    Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

    Alias Symbols: SLC25A7, UCP

    Protein Interaction Partner: CIDEA,TOMM20,TOMM20

    Protein Size: 307

    Poids moléculaire

    34 kDa

    ID gène

    7350

    NCBI Accession

    NM_021833, NP_068605

    UniProt

    P25874
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