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Pleiotrophin Produits

(Pleiotrophin (PTN))
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation (By similarity).

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Catégories Pleiotrophin en vedette

Pleiotrophin Anticorps

High quality antibodies with extensive validation data.

Pleiotrophin Kits ELISA

Reliable ELISA kits for a wide range of species.

Pleiotrophin Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Pleiotrophin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (8)
  • (5)
N° du produit ABIN562528
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7433426
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN656197
Quantité 400 μL
Fiche technique Fiche technique

Pleiotrophin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (4)
N° du produit ABIN6574270
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958661
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962237
Quantité 96 tests
Fiche technique Fiche technique

Pleiotrophin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275498
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320789
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316796
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Pleiotrophin

He, Boulant, Stanifer, Guo, Nießen, Chen, Felix, Bergmann, Strobel, Schimmack: "The link between menin and pleiotrophin in the tumor biology of pancreatic neuroendocrine neoplasms." dans: Cancer science, Vol. 113, Issue 5, pp. 1575-1586, (2022) (PubMed).

Wu, Xu, Bao, Gao, Chen, Zhang, Chen, Hong, Xue, Jiang, Liu, Huang, Sun, Fu, Li, Cui: "Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin." dans: The Journal of biological chemistry, Vol. 298, Issue 10, pp. 102443, (2022) (PubMed).

Hauser, Kaminski, Syring, Holdenrieder, Dieckmann, Muller, Ellinger: "Evaluation of Serum Biomarkers (FGF-2, HGF, MIF and PTN) in Patients With Testicular Germ Cell Cancer." dans: In vivo (Athens, Greece), Vol. 33, Issue 6, pp. 1935-1940, (2020) (PubMed).

Nikolakopoulou, Montagne, Kisler, Dai, Wang, Huuskonen, Sagare, Lazic, Sweeney, Kong, Wang, Owens, Lawson, Xie, Zhao, Zlokovic: "Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss." dans: Nature neuroscience, Vol. 22, Issue 7, pp. 1089-1098, (2019) (PubMed).

Wang, LeBlanc, Chen, Chen, Ji, Brewer, Tian, Spring, Webster, Li: "Pathogenic role and therapeutic potential of pleiotrophin in mouse models of ocular vascular disease." dans: Angiogenesis, Vol. 20, Issue 4, pp. 479-492, (2018) (PubMed).

Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." dans: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

Terkawi, Nishimura, Furuoka, Nishikawa: "Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice." dans: Infection and immunity, Vol. 84, Issue 3, pp. 845-55, (2016) (PubMed).

Zhu, Bai, Yu, Pan, Jin, Song, Xu, Yao, Huang, Tao, Li, Zhao: "The effects of pleiotrophin in proliferative diabetic retinopathy." dans: PLoS ONE, Vol. 10, Issue 1, pp. e0115523, (2015) (PubMed).

Koutsioumpa, Polytarchou, Courty, Zhang, Kieffer, Mikelis, Skandalis, Hellman, Iliopoulos, Papadimitriou: "Interplay between ?v?3 integrin and nucleolin regulates human endothelial and glioma cell migration." dans: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 343-54, (2013) (PubMed).

Kaspiris, Mikelis, Heroult, Khaldi, Grivas, Kouvaras, Dangas, Vasiliadis, Lioté, Courty, Papadimitriou: "Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis." dans: Joint, bone, spine : revue du rhumatisme, Vol. 80, Issue 4, pp. 407-13, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Pleiotrophin

pleiotrophin (ptn), pleiotrophin (PTN), pleiotrophin L homeolog (ptn.L), pleiotrophin (Ptn), harp, HARP, HB-GAM, HBBM, HBBN, HBGF-8, hbgf8, HBGF8, hbnf, HBNF, Hbnf, negf1, NEGF1, OSF, OSF-1, Osf-1, Osf1, ptn, PTN, PTN-A, X-PTF, zgc:111787, zHBNF

Protein level used designations for Pleiotrophin

  • heparin-binding neurite-promoting factor
  • pleiotrophin
  • pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
  • Pleiotrophin
  • HB-GAM
  • HBBM
  • HBGF-8
  • HBNF-1
  • OSF-1
  • heparin affin regulatory protein
  • heparin binding growth factor 8
  • heparin-binding brain mitogen
  • heparin-binding growth factor 8
  • heparin-binding growth-associated molecule
  • heparin-binding neurite outgrowth-promoting factor 1
  • neurite growth-promoting factor 1
  • osteoblast-specific factor 1
  • PTF-beta-1
  • X-PTF-beta1
  • pleiotrophic factor-beta-1
  • pleiotrophin-A
  • heparin-binding neutrophic factor
  • p18
  • heparin affin regulatory peptide
  • heparin-binding neurite promoting factor
  • heparin-binding neurotorphic factor
  • osteoblastic cell factor
  • Pleiotrophin (Heparine binding factor, Hbnf, in the mouse)
  • heparin binding factor
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