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PRDM2 Produits

(PR Domain Containing 2, with ZNF Domain (PRDM2))

Catégories

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

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Catégories PRDM2 en vedette

PRDM2 Anticorps

High quality antibodies with extensive validation data.

PRDM2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PRDM2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ChIP
Validations
  • (2)
  • (4)
N° du produit ABIN387783
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Rat
Application IHC
Validations
  • (5)
N° du produit ABIN7264615
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, ChIP
Validations
  • (6)
N° du produit ABIN3032300
Quantité 0.4 mL
Fiche technique Fiche technique

PRDM2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951135
Quantité 96 tests
Fiche technique Fiche technique

PRDM2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124542
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316143
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7317620
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PRDM2

Cheng, Gao, Lou: "DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer." dans: European journal of medical research, Vol. 15, Issue 1, pp. 20-4, (2010) (PubMed).

Harsløf, Husted, Carstens, Stenkjaer, Langdahl: "Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis." dans: Calcified tissue international, Vol. 87, Issue 1, pp. 25-35, (2010) (PubMed).

Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." dans: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).

de Vogel, Wouters, Gottschalk, van Schooten, de Goeij, de Bruïne, Goldbohm, van den Brandt, Weijenberg, van Engeland: "Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 11, pp. 3086-96, (2009) (PubMed).

Carling, Kim, Yang, Gu, Zhang, Huang: "A histone methyltransferase is required for maximal response to female sex hormones." dans: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à PRDM2

PR domain containing 2, with ZNF domain S homeolog (prdm2.S), PR domain containing 2, with ZNF domain b (prdm2b), PR domain containing 2, with ZNF domain (prdm2), PR domain zinc finger protein 2 (LOC100350859), PR/SET domain 2 (PRDM2), PR domain containing 2, with ZNF domain (Prdm2), PR/SET domain 2 (Prdm2), 4833427P12Rik, E330024L24Rik, Gm1033, Gm19732, humhoxy1, HUMHOXY1, kmt8, KMT8, MGC114763, mtb-zf, MTB-ZF, prdm2, PRDM2, riz, RIZ, Riz, riz1, RIZ1, Riz1, riz2, RIZ2, Znfpr1c1

Protein level used designations for PRDM2

  • PR domain containing 2, with ZNF domain
  • retinoblastoma protein-binding zinc finger protein-like
  • PR domain zinc finger protein 2-like
  • GATA-3 binding protein G3B
  • GATA-3-binding protein G3B
  • MTE-binding protein
  • PR domain zinc finger protein 2
  • PR domain-containing protein 2
  • lysine N-methyltransferase 8
  • retinoblastoma protein-binding zinc finger protein
  • retinoblastoma protein-interacting zinc finger protein
  • zinc finger protein RIZ
  • zinc-finger DNA-binding protein
  • retinoblastoma interacting zinc finger protein
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