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Premelanosome Protein Protéines

(Premelanosome Protein (PMEL))

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].

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Melanoma gp100 Protein (AA 1-661) (GST tag)

PMEL Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Premelanosome Protein (PMEL) (AA 1-661) protein (GST tag) (ABIN1320014)

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N° du produit ABIN1320014

Détails

Melanoma gp100 Protein (AA 25-595) (Fc Tag)

PMEL Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.