Prosaposin Produits
(Prosaposin (PSAP))
Catégories
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories Prosaposin en vedette
Prosaposin Anticorps
High quality antibodies with extensive validation data.
Prosaposin Kits ELISA
Reliable ELISA kits for a wide range of species.
Prosaposin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Prosaposin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (6)
N° du produit
ABIN1098150
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (10)
N° du produit
ABIN7435130
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (8)
N° du produit
ABIN7193617
Quantité
0.1 mg
Fiche technique
Fiche technique
Prosaposin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958859
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951184
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730233
Quantité
96 tests
Fiche technique
Fiche technique
Prosaposin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
N° du produit
ABIN1316504
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124603
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316506
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Prosaposin
: "Putative Biomarkers for Malignant Pleural Mesothelioma Suggested by Proteomic Analysis of Cell Secretome." dans: Cancer genomics & proteomics, Vol. 17, Issue 3, pp. 225-236, (2020) (PubMed).: "Prosaposin in seminal plasma on the day of oocyte retrieval is associated with normal fertilization and embryo development in in vitro fertilization cycles." dans: PeerJ, Vol. 7, pp. e8177, (2019) (PubMed).
: "Prosaposin is a regulator of progranulin levels and oligomerization. ..." dans: Nature communications, Vol. 7, pp. 11992, (2016) (PubMed).
: "Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer." dans: Breast cancer research : BCR, Vol. 17, Issue 1, pp. 123, (2015) (PubMed).
: "Decrease in prosaposin in spermatozoon is associated with polychlorinated biphenyl exposure." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 3, pp. 2436-48, (2015) (PubMed).
: "Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation." dans: The Journal of biological chemistry, Vol. 289, Issue 29, pp. 20026-38, (2014) (PubMed).
: "Serum prosaposin levels are increased in patients with advanced prostate cancer." dans: The Prostate, Vol. 72, Issue 3, pp. 253-69, (2012) (PubMed).
: "Prosaposin, a regulator of estrogen receptor alpha, promotes breast cancer growth." dans: Cancer science, Vol. 103, Issue 10, pp. 1820-5, (2012) (PubMed).
: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." dans: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." dans: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à Prosaposin
prosaposin (PSAP), prosaposin (Psap), prosaposin (psap), prosaposin (LOC100011417), prosaposin (LOC100304726), prosaposin (LOC100526719), surfactant protein A1 (SFTPA1), AI037048, cb759, GLBA, PSAP, PSP-A, SAP1, SFTPA1B, SGP-1, SGP1A, SP-A, wu:fa14a06, wu:fb36e02, wu:fb58g07Protein level used designations for Prosaposin
- proactivator polypeptide
- sphingolipid activator protein-1
- snoRNA MBII-198
- sulfated glycoprotein 1
- prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator)
- prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)
- prosaposin
- proactivator polypeptide-like
- pulmonary surfactant-associated protein A
- surfactant protein A
- surfactant protein A1B
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