AG-2 (AA 21-175) protein (His tag)

N° du produit ABIN1095972

Détail du produit

Antigène: AG-2

Type de proteíne: Recombinant

Attributs du protein: AA 21-175

Origine: Humain

Source: Human Cells

Purification/Conjugué: His tag

Fonction: Recombinant Human Anterior Gradient Protein 2 Homolog/AG-2/HPC8/AGR2 (C-6His)

Séquence: RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTELVDHHH HHH

Attributs du produit: Recombinant Human Anterior Gradient Protein 2 Homolog/AGR2 produced by transfected human cells is a secreted protein with sequence (Arg21-Leu175) of Human AGR2 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,200 mM NaCl,10 % Glycerol, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: AG-2

Synonymes: AG2 Protein, GOB-4 Protein, HAG-2 Protein, PDIA17 Protein, XAG-2 Protein, Agr2h Protein, Gob-4 Protein, mAG-2 Protein, anterior gradient 2, protein disulphide isomerase family member Protein, anterior gradient 2 Protein, AGR2 Protein, Agr2 Protein

Sub Type: Fusionprotein

Classe de substances: Viral Protein

Sujet: Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
Alternative Names: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2

Poids moléculaire: 18.85 kDa

UniProt: O95994