ATG3 Protein (AA 1-314)

N° du produit ABIN1096065

Cette protéine Recombinant ATG3 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour ATG3 Protein (AA 1-314) (ABIN1096065)

Antigène: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 1-314

Fonction: Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3

Séquence: GSMQNVINTV KGKALEVAEY LTPVLKESKF KETGVITPEE FVAAGDHLVH HCPTWQWATG EELKVKAYLP TGKQFLVTKN VPCYKRCKQM EYSDELEAII EEDDGDGGWV DTYHNTGITG ITEAVKEITL ENKDNIRLQD CSALCEEEED EDEGEAADME EYEESGLLET DEATLDTRKI VEACKAKTDA GGEDAILQTR TYDLYITYDK YYQTPRLWLF GYDEQRQPLT VEHMYEDISQ DHVKKTVTIE NHPHLPPPPM CSVHPCRHAE VMKKIIETVA EGGGELGVHM YLLIFLKFVQ AVIPTIEYDY TRHFTM

Attributs du produit: Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.

Conseil sur la manipulation: minimize freeze-thaw cycles

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Autre désignation: Ubiquitin-Like-Conjugating Enzyme ATG3/ATG3

Sujet: Alternative Names: Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96, ATG3, APG3, APG3LRecombinant Human Ubiquitin-Like-Conjugating Enzyme ATG3/ATG3 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-His287) of Human ATG3 fused with a 6His tag at the C-terminus.
Ubiquitin-Like-Conjugating Enzyme ATG3 (ATG3) is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. ATG3 as a E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. As an autocatalytic E2-like enzyme, ATG3 also can catalyzes the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

Poids moléculaire: 36 kDa

UniProt: Q9NT62

Pathways: Autophagy