FH Protein (AA 45-510)
Aperçu rapide pour FH Protein (AA 45-510) (ABIN1096693)
Antigène
Voir toutes FH ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 45-510
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Fonction
- Recombinant Human Fumarase/FH
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Séquence
- MASQNSFRIE YDTFGELKVP NDKYYGAQTV RSTMNFKIGG VTERMPTPVI KAFGILKRAA AEVNQDYGLD PKIANAIMKA ADEVAEGKLN DHFPLVVWQT GSGTQTNMNV NEVISNRAIE MLGGELGSKI PVHPNDHVNK SQSSNDTFPT AMHIAAAIEV HEVLLPGLQK LHDALDAKSK EFAQIIKIGR THTQDAVPLT LGQEFSGYVQ QVKYAMTRIK AAMPRIYELA AGGTAVGTGL NTRIGFAEKV AAKVAALTGL PFVTAPNKFE ALAAHDALVE LSGAMNTTAC SLMKIANDIR FLGSGPRSGL GELILPENEP GSSIMPGKVN PTQCEAMTMV AAQVMGNHVA VTVGGSNGHF ELNVFKPMMI KNVLHSARLL GDASVSFTEN CVVGIQANTE RINKLMNESL MLVTALNPHI GYDKAAKIAK TAHKNGSTLK ETAIELGYLT AEQFDEWVKP KDMLGPK
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Attributs du produit
- Recombinant Human Fumarase/FH is produced by our E. coli expression system. The target protein is expressed with sequence (Ala45-Lys510) of Human FH.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.
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Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Stock
- -80 °C
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Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
Date de péremption
- 6 months
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- FH (Fumarate Hydratase (FH))
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Autre désignation
- Fumarase
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Sujet
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Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic form and N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.
Alternative Names: Fumarate Hydratase Mitochondrial, Fumarase, FH -
Poids moléculaire
- 50.2 kDa
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UniProt
- P07954
Antigène
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