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IFN alpha 2b Protein (Arg46)

Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Func Active
N° du produit ABIN1096852
  • Antigène Tous les produits IFN alpha 2b
    IFN alpha 2b
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    Arg46
    Origine
    Humain
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func)
    Fonction
    Recombinant Human Interferon α2B Variant (Arg46)/IFN-α2B
    Séquence
    MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
    Attributs du produit
    Recombinant Human Interferon-alpha2b produced in E. coli is a single non-glycosylated polypeptide chain containing 166 amino acids with a molecular mass of 19,4 kDa. The Interferon-alpha2b gene was obtained from human leukocytes.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Commentaires

    Biological activity: Specific Activity is greater than 1.0 x 108 IU/ mg as determined by a viral resistance assay using VSV-WISH cells.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    IFN alpha 2b
    Autre désignation
    IFN-alpha 2B (IFN alpha 2b Produits)
    Synonymes
    IFN-alphaA Protein, IFNA Protein, IFNA2B Protein, INFA2 Protein, interferon alpha 2 Protein, IFNA2 Protein
    Sujet
    At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.
    Alternative Names: Interferon Alpha-2, IFN-Alpha-2, Interferon Alpha-A, LeIF A, IFNA2
    Poids moléculaire
    19.4 kDa
    UniProt
    P01563
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