VEGF Protein (AA 27-191)
Aperçu rapide pour VEGF Protein (AA 27-191) (ABIN1097784)
Antigène
Voir toutes VEGF ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 27-191
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Fonction
- Recombinant Human VEGF-A/VEGF165
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Séquence
- APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
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Attributs du produit
- Recombinant Human VEGF 165 (Vascular Endothelial Growth Factor Isoform 165) was produced in human cells that were transfected with an expression plasmid encoding Human VEGF165 (Ala27-Arg191).
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Stock
- 4 °C/-20 °C/-80 °C
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Stockage commentaire
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
Date de péremption
- 3 months
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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Autre désignation
- Vegf
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Sujet
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Recombinant Human VEGF 165: Human Vascular endothelial growth factor, also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
Alternative Names: Recombinant Human VEGF 165, Vascular Endothelial Growth Factor Isoform 165, VEGF165 -
Poids moléculaire
- 19.1 kDa
Antigène
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