Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag)
Aperçu rapide pour Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag) (ABIN1098613)
Antigène
Voir toutes Glucose-6-Phosphate Dehydrogenase (G6PD) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Glucose-6-Phosphate Dehydrogenase protéine est marqué à la His tag.
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Purification
- purified by using conventional chromatography.
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Commentaires
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Synonyms: glucose-6-phosphate 1-dehydrogenase, G6PD1
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/ml (determined by Bradford assay)
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Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 MM PMSF, 2 mM EDTA, 2 mM DTT, 200 mM NaCl
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Stock
- 4 °C
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Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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Autre désignation
- G6PD
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Sujet
- Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia. Recombinant human G6PD protein, fused to His-tag at N-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
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Poids moléculaire
- 61.4kDa (535aa)
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NCBI Accession
- NP_001035810
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Antigène
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