CD161 Protein (His tag)

N° du produit ABIN1098668

Détail du produit

Antigène: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CD161 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Killer cell lectin-like receptor subfamily B member 1, p35-2, STX4A

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Autre désignation: KLRB1 (KLRB1 Produits)

Synonymes: NKR-P1 Protein, KLRB1 Protein, 4930431A04Rik Protein, Gm4696 Protein, Klrb1g Protein, Klrb6 Protein, Ly-55 Protein, Ly55 Protein, NKR-P1G Protein, Nkrp-1e Protein, Nkrp1g Protein, CD161 Protein, CLEC5B Protein, NKR Protein, NKR-P1A Protein, NKRP1A Protein, hNKR-P1A Protein, Klrb1d Protein, Klrb1f Protein, Nkr-p1e Protein, killer cell lectin like receptor B1 Protein, killer cell lectin-like receptor subfamily B member 1 Protein, killer cell lectin-like receptor subfamily B, member 1 Protein, KLRB1 Protein, Klrb1 Protein

Sujet: Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 21.0 kDa (183aa)

NCBI Accession: NP_002249