PROX1 Protein (partial)
Aperçu rapide pour PROX1 Protein (partial) (ABIN1589681)
Antigène
Voir toutes PROX1 ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- partial
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Fonction
- Prox-1 (fragment)
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Séquence
- MAEGLSLSLI KSECGDLQDM SEISPYSGSA MQEGLSPNHL KKAKLMFFYT RYPSSNMLKT YFSDVKFNRC ITSQLIKWFS NFREFYYIQM EKYARQAIND GVTSTEELSI TRDCELYRAL NMHYNKANDF EVPERFLEVA QITLREFFNA IIAGKDVDPS WKKAIYKVIC KLDSEVPEIF KSPNCLQELL HE
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Specificité
- Chromosomal location:1q32.2-q32.3
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Attributs du produit
- Length (aa):192
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Indications d'application
- Control for Western Blotting. Biological activity not tested.
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Commentaires
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Cytokines & Growth Factors
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge vial prior to opening. The lyophilized Prox-1 should be reconstituted in water to a concentration not lower than 50 μg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- RT,-20 °C
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Stockage commentaire
- The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted Prox-1 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
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- PROX1 (Prospero Homeobox 1 (PROX1))
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Autre désignation
- Prox-1
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Sujet
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Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. The highly conserved C-terminal part of the homeobox transcription factor Prox1 was produced in E. coli. It was not tested for activity and can be used as positive control e.g. in Western analysis.
Synonyms: PROX1, W117m -
Poids moléculaire
- 22.35 kDa
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ID gène
- 5629
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NCBI Accession
- NM_002763, NP_002754
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UniProt
- Q92786
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
Antigène
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