Peroxiredoxin 3 Protein (PRDX3) (AA 63-256)
Aperçu rapide pour Peroxiredoxin 3 Protein (PRDX3) (AA 63-256) (ABIN1692321)
Antigène
Voir toutes Peroxiredoxin 3 (PRDX3) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 63-256
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Fonction
- Recombinant Human Peroxiredoxin-3/PRDX3
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Séquence
- MPAVTQHAPY FKGTAVVNGE FKDLSLDDFK GKYLVLFFYP LDFTFVCPTE IVAFSDKANE FHDVNCEVVA VSVDSHFSHL AWINTPRKNG GLGHMNIALL SDLTKQISRD YGVLLEGSGL ALRGLFIIDP NGVIKHLSVN DLPVGRSVEE TLRLVKAFQY VETHGEVCPA NWTPDSPTIK PSPAASKEYF QKVNQ
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Attributs du produit
- Recombinant Human Thioredoxin-Dependent Peroxide Reductase Mitochondrial/PRDX3 is produced with our E. coli expression system. The target protein is expressed with sequence (Pro63-Gln256) of Human PRDX3.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
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Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Stock
- -80 °C
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Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
Date de péremption
- 6 months
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- Peroxiredoxin 3 (PRDX3)
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Autre désignation
- PRDX3
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Sujet
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Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Alternative Names: Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1 -
Poids moléculaire
- 21.6 kDa
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UniProt
- P30048
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Antigène
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