Endoglin Protein (ENG) (AA 26-176) (His-TRX)
Aperçu rapide pour Endoglin Protein (ENG) (AA 26-176) (His-TRX) (ABIN1692461)
Antigène
Voir toutes Endoglin (ENG) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 26-176
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Purification/Conjugué
- Cette Endoglin protéine est marqué à la His-TRX.
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Fonction
- Recombinant Human Endoglin/CD105 (N-Trx, 6His)
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Séquence
- MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ETVHCDLQPV GPERDEVTYT TSQVSKGCVA QAPNAILEVH VLFLEFPTGP SQLELTLQAS KQNGTWPREV LLVLSVNSSV FLHLQALGIP LHLAYNSSLV TFQEPPGVNT TELPSFPKTQ ILEWAAERGP ITSAAELNDP QSILLRLGQA Q
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Attributs du produit
- Recombinant Human Endoglin is produced by our E.coli expression system and the target gene encoding Glu26-Gln176 is expressed with a Trx, 6His tag at the N-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Conseil sur la manipulation
- minimize freeze-thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Date de péremption
- 6 months
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- Endoglin (ENG)
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Autre désignation
- Endoglin
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Sub Type
- Fusionprotein
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Sujet
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Alternative Names: Endoglin, END, CD105, ENGEndoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.
Alternative Names: Endoglin, END, CD105, ENG -
Poids moléculaire
- 33.6 kDa
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UniProt
- P17813
Antigène
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