Cytokeratin 19 Protéine

N° du produit ABIN1880333

Cette protéine Native Cytokeratin 19 est produite dans Human.

Aperçu rapide pour Cytokeratin 19 Protéine (ABIN1880333)

Antigène: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Type de proteíne: Native

Origine: Humain

Source: Human

Détail du produit

Purification: Purified

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Tris-HCl (pH 7.4 +/- 0.2) with 0.2 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C

Détail du antigène

Antigène: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Autre désignation: Cytokeratin 19

Sujet: Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. It has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis. The low-molecular-weight cytokeratin (CK) protein CK19 has been shown to have diagnostic use and prognostic significance in some types of human malignancy. Cytokeratin-19 alone and its combinations with other markers were more sensitive in accurate diagnosis of papillary carcinoma than the other combinations.