C-Peptide Protéine

N° du produit ABIN1880359

Protéine Recombinant C-Peptide exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour C-Peptide Protéine (ABIN1880359)

Antigène: C-Peptide

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % by HPLC & SDS-PAGE

Détail du produit

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10mM PBS (pH 7.5)

Agent conservateur: Without preservative

Stock: 4 °C

Détail du antigène

Antigène: C-Peptide

Sujet: Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.