PGC Pepsinogen II (Active) Protéine

N° du produit ABIN1880433

Cette protéine Recombinant PGC Pepsinogen II est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour PGC Pepsinogen II (Active) Protéine (ABIN1880433)

Antigène: PGC Pepsinogen II

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Application: ELISA, SDS-PAGE (SDS)

Pureté: >95 % by SDS-PAGE

Détail du produit

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Tris-HCl( pH 7.4±0.2) with 0.2 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: PGC Pepsinogen II

Sujet:

Synonyms: Gastricsin, Pepsinogen C, PGC

Description: Recombinant full length human PG II protein with molecular weight 42 kDa.

Background: Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41-amino acid segment from the amino end. There are 2 related pepsinogen systems in man: PGA, formerly PG I, precursor of pepsin A, and PGC, formerly PG II, precursor of pepsin C. In human gastric mucosa, 2 immunologically distinct classes of pepsinogen are synthesized. PG1 is restricted to the corpus, while PG2 is found throughout the stomach as well as in the proximal duodenum. PG1 is found in serum and urine in a ratio of about 1 to 10. PG2 is present in serum and seminal fluid but only trace amounts are found in urine. Serum PG1 and PG2 apparently originate from the stomach in the main, because the levels are very low after gastrectomy. PG2 in seminal fluid probably originates from the prostate.

Poids moléculaire: 42 kDa