MMP12 Protein (AA 106-267, Catalytic Domain)
-
- Antigène Voir toutes MMP12 Protéines
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 106-267, Catalytic Domain
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Attributs du produit
- The sequence corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. Coli.
- Purification
- Purified from bacterial lysate and refolded using proprietary technique.
- Top Product
- Discover our top product MMP12 Protéine
-
-
- Restrictions
- For Research Use only
-
- Stock
- -80 °C
-
- Antigène
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Autre désignation
- MMP-12 (MMP12 Produits)
- Synonymes
- MMP12 Protein, AV378681 Protein, Mmel Protein, Mme Protein, HME Protein, ME Protein, MME Protein, MMP-12 Protein, matrix metallopeptidase 12 Protein, MMP12 Protein, Mmp12 Protein
- Sujet
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54 kDa zymogen and becomes the mature 54 kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including alpha-1 proteinase inhibitor, alpha-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.
- Poids moléculaire
- 18 kDa
- NCBI Accession
- NP_002417
-