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ADIPOQ Protein (AA 21-247)

Protéine Recombinant ADIPOQ exprimée dans Escherichia coli (E. coli).
N° du produit ABIN2017656

Aperçu rapide pour ADIPOQ Protein (AA 21-247) (ABIN2017656)

Antigène

Voir toutes ADIPOQ Protéines
ADIPOQ (Adiponectin (ADIPOQ))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 26
  • 19
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Souris

Source

  • 32
  • 9
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Pureté

> 95 % as analyzed by SDS-PAGE and HPLC.
  • Attributs du protein

    AA 21-247

    Attributs du produit

    ED50 < 5 μg/mL, measured by a cell growth inhibitory assay using M1 cells, corresponding to a specific activity of > 2x 10^2 units/mg.

    niveau d'endotoxine

    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstituted in ddH2O at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Stock

    -80 °C

    Stockage commentaire

    Lyophilized recombinant mouse Adiponectin (rmAdiponectin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmAdiponectin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    Date de péremption

    6 months
  • Antigène

    ADIPOQ (Adiponectin (ADIPOQ))

    Autre désignation

    Adiponectin

    Sujet

    Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. The receptors of Adiponectin are seven transmembrane G protein coupled receptors: Receptor 1 is expressed in skeletal muscle and Receptor 2 in liver. Adiponectin receives a lot of attention because of its anti-diabetic, anti-atherosclerotic, and anti-inflammatory properties. Adiponectin increases the expression of molecules involved in fatty acid transport, combustion of fatty acid, and energy dissipation, and increases insulin sensitivity of the body. Decreased levels of Adiponectin are associated with hypertension, cardiovascular diseases, and metabolic syndromes. Therefore, Adiponectin has promising potential as a pharmacological agent.Recombinant mouse Adiponectin (rmAdiponectin) produced in E. coli is a single non-glycosylated polypeptide chain containing 227 amino acids. A fully biologically active molecule, rmAdiponectin has a molecular mass of 24.6 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Acrp-30, GBP-28, Apm-1

    Poids moléculaire

    24.6 kDa, observed by reducing SDS-PAGE.

    UniProt

    Q60994
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