IFNW1 Protéine
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- Antigène Voir toutes IFNW1 (IFNW) Protéines
- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Séquence
- CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
- Attributs du produit
- Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/mL, corresponding to a specific activity of > 1.0 x 10^8 IU/mg.
- Pureté
- > 97 % by SDS-PAGE and HPLC analyses.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- < 1 EU/μg of rHuIFN-μ as determined by LAL method.
- Top Product
- Discover our top product IFNW Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Buffer
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- Antigène
- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
- Autre désignation
- Interferon omega (IFNW Produits)
- Synonymes
- IFNW1 Protein, interferon omega 1 Protein, interferon, omega 1 Protein, inteferon omega 1 Protein, IFNW1 Protein, LOC100155760 Protein, IFN-OMEGA1 Protein
- Sujet
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Interferon-Omega (IFN-o) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-a, IFN-b, and IFN-o. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or the antiproliferative actions. IFN-omega is derived from IFN-a/b and share 75 % sequence with IFN-a. It has two intramolecular disulfide bonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-a, IFN-b, and IFN-o that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1 cells, or Epo and Epo-transfected UT-7 cells.
Synonyms: IFN Omega Human - Poids moléculaire
- 20.0 kDa, containing 172 amino acid residues with two conserved disulfide bonds.
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