IL-10 Protein (AA 19-178)
Aperçu rapide pour IL-10 Protein (AA 19-178) (ABIN2018051)
Antigène
Voir toutes IL-10 (IL10) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 19-178
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Attributs du produit
- ED50 < 0.2 ng/mL, measured in a cell proliferation assay using MC/9 cells.
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niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 10 (IL10) (AA 19-178) protein (His-Avi Tag)
IL10 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 (IL10) (AA 19-178) protein (His-Avi Tag,Biotin)IL10 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 10 (IL10) (Active) proteinIL10 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 10 (IL10) (AA 22-178) protein (His tag)IL10 Origine: Hamster Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 10 (IL10) (AA 19-178) proteinIL10 Origine: Humain Hôte: Mammalian Cells Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 10 (IL10) (AA 19-178) (Active) protein (His tag)IL10 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 10 (IL10) (AA 1-178) protein (GST tag)IL10 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 10 (IL10) (AA 19-178) (Active) protein (His tag)IL10 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 10 (IL10) proteinIL10 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 10 (IL10) (AA 19-178) protein (His tag)IL10 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Stock
- -80 °C
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Stockage commentaire
- Lyophilized recombinant Human Interleukin-10 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-10 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Date de péremption
- 6 months
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- IL-10 (IL10) (Interleukin 10 (IL10))
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Autre désignation
- Interleukin-10(IL-10)
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Sujet
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Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80 % sequence homology with Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells, and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells. It also displays ability to suppress Antigen-Presenting Cell (APC) function. The net effect of Interleukin-10 appears to be inhibitory, however, stimulatory effects, such as stimulation of B cell maturation and antibody production, are also reported.
Synonyms: B-TCGF, CSIF, TGIF -
Poids moléculaire
- 18-19 kDa, observed by reducing SDS-PAGE.
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UniProt
- P22301
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
Antigène
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