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NOG Protein (AA 28-232)

NOG Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
N° du produit ABIN2018291
  • Antigène Voir toutes NOG Protéines
    NOG (Noggin (NOG))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 28-232
    Origine
    • 14
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Source
    • 19
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    CHO Cells
    Attributs du produit
    ED50<2.5 ng/mL, measured in a bioassay using ATDC5 cells in the presence of 10 ng/mL human BMP-4.
    Pureté
    > 95 % as analyzed by SDS-PAGE.
    niveau d'endotoxine
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product NOG Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Stock
    -80 °C
    Stockage commentaire
    Lyophilized recombinant human Noggin remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human Nogginshould be stable up to 1 week at 4°C or up to 2 months at -20°C.
    Date de péremption
    6 months
  • Antigène
    NOG (Noggin (NOG))
    Autre désignation
    Noggin (NOG Produits)
    Synonymes
    SYM1 Protein, SYNS1 Protein, nog-A Protein, nog1 Protein, noggin-1 Protein, noggin Protein, noggin Protein, noggin L homeolog Protein, noggin protein Protein, NOG Protein, Nog Protein, nog.L Protein, noggin Protein
    Sujet
    Noggin, also known as NOG, is a homodimeric glycoprotein that bindsto and modulates the activity of TGF-beta family ligands. It is expressed in condensing cartilage and immature chondrocytes. Noggin antagonizes bone morphogenetic protein (BMP) activities by blocking epitopes on BMPs needed for binding to their receptors. Noggin has been shown to be involved in many developmental processes, such as neural tube formation and joint formation. During development, Noggin diffuses through extracellular matrices and forms morphogenic gradients, regulating cellular responses dependent on the local concentration of the signaling molecule.
    Synonyms: NOG
    Poids moléculaire
    29-31kDa, observed by reducing SDS-PAGE.
    UniProt
    Q13253
    Pathways
    Stem Cell Maintenance, Tube Formation
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