PF4 Protein (AA 32-101)

N° du produit ABIN2018316

Cette protéine Recombinant PF4 est produite dans HEK-293T Cells.

Aperçu rapide pour PF4 Protein (AA 32-101) (ABIN2018316)

Antigène: PF4 (Platelet Factor 4 (PF4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293T Cells

Pureté: > 95 % as analyzed by SDS-PAGE and HPLC.

Détail du produit

Attributs du protein: AA 32-101

Attributs du produit: ED50 < 10 μg/mL, measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant human platelet factor 4 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human platelet factor 4 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: PF4 (Platelet Factor 4 (PF4))

Autre désignation: Platelet Factor 4/CXCL4

Sujet: Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the alpha-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Synonyms: PF-4, CXCL4, SCYB4,Platelet Factor-4, CXCL4, Oncostatin A, Ironplact

Poids moléculaire: -7.8 kDa, observed by non-reducing SDS-PAGE.

UniProt: P02776