PF4 Protein (AA 32-101)
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- Antigène Voir toutes PF4 Protéines
- PF4 (Platelet Factor 4 (PF4))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 32-101
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Origine
- Humain
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Source
- HEK-293T Cells
- Attributs du produit
- ED50 < 10 μg/mL, measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Platelet Factor 4 (PF4) (AA 32-101) protein (Fc Tag)
PF4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Factor 4 (PF4) (AA 30-105) protein (Fc Tag)PF4 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag)PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag,Biotin)PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 1-101) protein (GST tag)PF4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Factor 4 (PF4) (AA 31-101) protein (GST tag)PF4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Factor 4 (PF4) (AA 48-101) protein (His tag)Crystallography grade PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Platelet Factor 4 (PF4) (AA 32-101) protein (His tag)Crystallography grade PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant human platelet factor 4 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human platelet factor 4 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- PF4 (Platelet Factor 4 (PF4))
- Autre désignation
- Platelet Factor 4/CXCL4 (PF4 Produits)
- Synonymes
- CXCL4 Protein, PF-4 Protein, SCYB4 Protein, Cxcl4 Protein, Scyb4 Protein, Pf4a Protein, RATPF4A Protein, PF4A Protein, CXCL4L1 Protein, CXCL4V1 Protein, PF4-ALT Protein, SCYB4V1 Protein, PF4 Protein, platelet factor 4 Protein, platelet factor 4 variant 1 Protein, PF4 Protein, Pf4 Protein, LOC703451 Protein, PF4V1 Protein, LOC100524373 Protein, LOC102181854 Protein, LOC100630489 Protein
- Sujet
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Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the alpha-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Synonyms: PF-4, CXCL4, SCYB4,Platelet Factor-4, CXCL4, Oncostatin A, Ironplact - Poids moléculaire
- -7.8 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- P02776
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