Thyroperoxidase Protein (full length)

N° du produit ABIN2132174

Cette protéine Recombinant Thyroperoxidase est produite dans Insect cells (Sf9).

Aperçu rapide pour Thyroperoxidase Protein (full length) (ABIN2132174)

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Application: Western Blotting (WB), ELISA

Pureté: > 95 % pure

Détail du produit

Attributs du protein: full length

Attributs du produit: Purified recombinant Human Thyroid Peroxidase protein
Expression System: Sf-9 insect cells

Purification: Proprietary chromatographic technique

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détail du antigène

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: Thyroid Peroxidase

Sujet: Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
Alternative Names: TPX protein, MSA protein, TPO protein

Poids moléculaire: 101 kDa

Pathways: Thyroid Hormone Synthesis