Thyroperoxidase Protein (full length)
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- Antigène Voir toutes Thyroperoxidase (TPO) Protéines
- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
- Type de proteíne
- Recombinant
- Attributs du protein
- full length
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Origine
- Humain
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Source
- Insect cells (Sf9)
- Application
- Western Blotting (WB), ELISA
- Attributs du produit
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Purified recombinant Human Thyroid Peroxidase protein
Expression System: Sf-9 insect cells - Purification
- Proprietary chromatographic technique
- Pureté
- > 95 % pure
- Top Product
- Discover our top product TPO Protéine
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Antigène
- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
- Autre désignation
- Thyroid Peroxidase (TPO Produits)
- Synonymes
- MSA Protein, TDH2A Protein, TPX Protein, TPO Protein, msa Protein, tpx Protein, xtpo Protein, LOC100218312 Protein, thyroid peroxidase Protein, TPO Protein, Tpo Protein, tpo Protein, LOC100547103 Protein
- Sujet
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Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
Alternative Names: TPX protein, MSA protein, TPO protein - Poids moléculaire
- 101 kDa
- Pathways
- Thyroid Hormone Synthesis
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