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Thyroperoxidase Protein (full length)

TPO Origine: Humain Hôte: Insect cells (Sf9) Recombinant > 95 % pure WB, ELISA
N° du produit ABIN2132174
  • Antigène Voir toutes Thyroperoxidase (TPO) Protéines
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Type de proteíne
    Recombinant
    Attributs du protein
    full length
    Origine
    • 9
    • 6
    • 2
    Humain
    Source
    • 6
    • 5
    • 3
    • 2
    • 1
    Insect cells (Sf9)
    Application
    Western Blotting (WB), ELISA
    Attributs du produit
    Purified recombinant Human Thyroid Peroxidase protein
    Expression System: Sf-9 insect cells
    Purification
    Proprietary chromatographic technique
    Pureté
    > 95 % pure
    Top Product
    Discover our top product TPO Protéine
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Antigène
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Autre désignation
    Thyroid Peroxidase (TPO Produits)
    Synonymes
    MSA Protein, TDH2A Protein, TPX Protein, TPO Protein, msa Protein, tpx Protein, xtpo Protein, LOC100218312 Protein, thyroid peroxidase Protein, TPO Protein, Tpo Protein, tpo Protein, LOC100547103 Protein
    Sujet
    Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
    Alternative Names: TPX protein, MSA protein, TPO protein
    Poids moléculaire
    101 kDa
    Pathways
    Thyroid Hormone Synthesis
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